Advanced Search
Current and Breaking News for Professionals, Consumers and Media



Click here to learn how to advertise on this site and for ad rates.

Babies Author: Staff Editor Last Updated: Nov 22, 2017 - 10:49:02 AM



High-Fat Diet May Change Breast Milk Makeup, Affect Baby's Health

By Staff Editor
Nov 22, 2017 - 10:43:42 AM



Email Newsletter icon, E-mail Newsletter icon, Email List icon, E-mail List icon Sign up for our Ezine
For Email Marketing you can trust


Email this article
 Printer friendly page

(HealthNewsDigest.com) - Bethesda, Md. —New research suggests that following a high-fat diet during lactation—regardless of diet during pregnancy—alters RNA activity in breast milk. The changes in genetic material may increase the risk of metabolic disorders such as type 2 diabetes in offspring.  The article is published ahead of print in Physiological Genomics.

RNA is a molecule chain that uses genetic information from DNA—the “genetic blueprint”—to produce proteins in the cells. RNA defects can play a role in potentially serious health conditions such as cancer, heart disease and stroke.

Previous studies have shown that offspring born to mothers who consumed a high-fat diet during pregnancy and breastfeeding are more likely to become obese and develop chronic conditions such as diabetes, high blood pressure and heart disease. However, less is known about the effects of a high-fat diet during lactation alone.

Researchers from Purdue University in Indiana studied two groups of pregnant mice. One group was given a high-fat diet during gestation and the other was fed a typical diet. The research team divided the newborn mice pups into four groups:

  • born to and fed by mothers that followed a high-fat diet;
  • born to mothers that followed a high-fat diet and fed by mothers that followed a typical diet;
  • born to typical-diet mothers and fed by high-fat-diet mothers; and
  • born to and fed by normal-diet mothers.

The researchers found that the milk made by mice following a high-fat diet had a higher fat content. In addition, the researchers observed changes in both messenger RNA (mRNA), which delivers coded information from DNA to protein-making cells, and miRNA—non-coded genetic material involved with metabolism, cell death and nervous system function. More than 1,500 mRNA genes and 25 miRNAs expressed differently in the milk of the mothers on a high-fat diet during lactation compared to the milk produced by mothers on a typical diet. These changes could potentially affect the development of the newborns and put them at higher risk for chronic disease as adults. “Further, miRNA and mRNA only make up a portion of RNAs secreted in the milk and future studies will be needed to describe other species of RNAs [in breast milk] and their potential roles,” the researchers wrote.

Read the full article, “The effect of high fat diet on secreted milk transcriptome in mid-lactation mice,” published ahead of print in Physiological Genomics.

NOTE TO JOURNALISTS: To schedule an interview with a member of the research team, please contact the APS Communications Office or 301-634-7209. Find more research highlights in the APS Press Room.

Physiology is the study of how molecules, cells, tissues and organs function in health and disease. Established in 1887, the American Physiological Society (APS) was the first U.S. society in the biomedical sciences field. The Society represents more than 10,500 members and publishes 15 peer-reviewed journals with a worldwide readership.



Top of Page

HealthNewsDigest.com

Babies
Latest Headlines


+ Recordings Reveal Deep Credibility Gap When Doctors And Parents Discuss Outcomes For Critically Ill Infants
+ High-Fat Diet May Change Breast Milk Makeup, Affect Baby's Health
+ Sperm RNA May Serve as Biomarkers of Future Health
+ Living in a ‘War Zone’ Linked to Delivery of Low Birthweight Babies
+ Removing Chemical Used to Make Teflon-like Coatings Has Led to Fewer Low Birth Weights and Less Brain Damage
+ High-Fat Diet May Change Breast Milk Makeup, Affect Baby's Health
+ For Infants with Certain Forms of Heart Disease, Are Shunts or Stents Better to Maintain Blood Flow Until Surgery?
+ Global Birth Season Study Links Environment with Disease Risk
+ Bacteria May Help Babies’ Digestive Tracts More Than Suspected, Scientists Find



Contact Us | Job Listings | Help | Site Map | About Us
Advertising Information | HND Press Release | Submit Information | Disclaimer

Site hosted by Sanchez Productions