Doctor 'chagrin' Among Reasons Why Antibiotics May be Overused at Hospitals
Mar 4, 2014 - 2:27:05 PM

As new CDC report shows potential harmful overuse of antibiotic prescriptions in hospitals, commentary sheds light on why too many may be doled out

( - ANN ARBOR, Mich. -  One reason doctors may prescribe antibiotics more often than necessary is because they want to avoid withholding a prescription from a hospitalized patient ultimately found to have a bacterial infection, University of Michigan doctors say in a new commentary.

The article, which appears in the Journal of the American Medical Association Internal Medicine, coincides with a report released by the Centers for Disease Control and Prevention today highlighting concerns over an overuse of antibiotics.

The CDC called on hospitals to evaluate their antibiotic practices in light of the findings that showed clinicians in some hospitals prescribe as many as three times more antibiotics than others.

Overuse of antibiotics leads to the development of bacterial resistance and puts patients at risk for serious infections such as severe diarrheal infection due to Clostridium difficile (C Diff).

"In medicine, there's a tendency to think there's no harm in erring on the side of caution - but in this case, it may sometimes put patients at risk," says lead author Scott Flanders, M.D., M.H.M, professor of internal medicine and director of hospital medicine at the U-M Medical School.

"Antibiotics, while incredibly beneficial, are unique because they also have the potential to harm other patients through the spread of C.diff and the development of bacteria resistance."

Flanders co-authored the JAMA paper with Sanjay Saint, M.D., M.P.H., the University of Michigan's George Dock professor of internal medicine and the associate chief of medicine at the VA Ann Arbor Healthcare System. The article is titled "Why does antimicrobial overuse in hospitalized patients persist?"

"When it's not clear whether a patient actually has an infection and treatment decisions are based on an educated guess, no one wants to discover days later that they guessed wrong. We call this the ‘chagrin factor,'" says Saint. "U.S. physicians tend to place the interests of their patients above the broader interests of society.  We need to provide physicians with strategies that are viewed as both benefiting the patient and society."

Both Flanders and Saint are members of the Institute for Healthcare Policy and Innovation.The authors recommend several strategies to improve antibiotic use at hospitals:


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