Advanced Search
Current and Breaking News for Professionals, Consumers and Media




Children's Health Author: staff Editor Last Updated: Apr 30, 2021 - 6:44:17 AM



Kids' Future Cardiovascular Health Threatened by Auto Emissions

By staff Editor
Apr 30, 2021 - 6:37:31 AM



Email Newsletter icon, E-mail Newsletter icon, Email List icon, E-mail List icon Sign up for our Ezine
For Email Marketing you can trust


Email this article
 Printer friendly page

(HealthNewsDigest.com) - Daily exposure to auto emissions during childhood may set the stage for cardiovascular disease in later life, according to a USC Children’s Health Study that followed 70 children into young adulthood.

The research, published recently in the journal Environmental Health, used ultrasound to examine the carotid arteries in participants at age 10 and again a decade later. Changes in carotid artery intima-media thickness, or CIMT, is a measure of very early-stage atherosclerosis, the underlying cause of most cardiovascular disease.

“Air pollution exposure has been strongly linked to adverse cardiovascular effects in adults. However, relatively few studies have examined the impact of air pollutants on the cardiovascular health of children and young adults,” said lead author Shohreh Farzan, an environmental epidemiologist at the Keck School of Medicine of USC. “To our knowledge, ours is the first study to evaluate changes in CIMT during the important transition from childhood to early adulthood.”

Launched in 1993 in Los Angeles — the city with the worst smog in the nation — the Children’s Health Study is one of the largest and most comprehensive investigations of the long-term effects of air pollution on the respiratory health of children.

The latest study drew from the most recent cohort of the Children’s Health Study: approximately 5,000 children from kindergarten and first grade in 2002-2003. Children in the current study came from 13 communities in Southern California, representing a mixture of neighborhood settings.

For each child, the researchers calculated average residential exposures to ambient, regional pollutants such as ozone, nitrogen dioxide and particulate matter by using regulatory air monitoring data. They estimated exposure to nitrogen oxides based on the proximity of a child’s home to busy freeways.

Nitrogen oxides, which include nitrogen dioxide, are a family of poisonous gases. Most nitrogen oxides are formed when fuel is burned at high temperatures in cars, trucks and power plants.

Tiny measurement may indicate future trouble

The researchers measured CIMT in microns per year, once in 2007-2008 when the children were 10 or 11 years old and again a decade later in 2018-2019. Though tiny in scale — a strand of human hair measures 17 to 181 microns in diameter — CIMT is a widely used measurement associated with risk of heart attacks and strokes.

Traffic-related exposures were associated with a 1.7 micron per year change in CIMT in these young adults, which roughly equals the change in CIMT previously observed in adolescents with an increase of 10 mm Hg of systolic blood pressure, a known cardiovascular risk factor.

“We found that greater exposures to pollutants in auto emissions, like nitrogen oxides, and greater traffic density in childhood were linked to greater yearly increases in CIMT from childhood to adulthood,” Farzan said.

Farzan noted that future studies will provide a fuller picture of the interplay between diet, physical activity and pollution exposure.

Early detection of carotid artery changes has the potential to improve understanding of how cardiovascular disease develops over time in relation to air pollution, Farzan said, and to help identify children at risk for cardiovascular disease as adults.

About the study

In addition to Farzan, the study’s authors are Rima Habre, Phoebe Danza, James Gauderman, Edward Avol, Theresa Bastain, Howard Hodis and Carrie Breton, all of the Department of Preventive Medicine at the Keck School of Medicine; and Frederick Lurmann of Sonoma Technology Inc.

The research was supported by grants from the National Institutes of Health (UH3OD023287) and pilot grants from the Southern California Environmental Sciences Center (P30ES007048) and the Southern California Clinical and Translational Sciences Institute (NIH NCATS grants UL1TR001855 and UL1TR000130). Farzan is also supported by a NIEHS Pathway to Independence Grant (R00 ES024144).



Top of Page

HealthNewsDigest.com

Children's Health
Latest Headlines


+ Helping Children Cope with School Shooting
+ Deaf Children with Learning Delays Benefit From Cochlear Implants
+ Provide Antibody Testing to Help Study Long COVID in Children 
+ New Resources for Clean and Healthy Child Care
+ Do Early Therapies Aid Very Young Children With or at High Likelihood for Autism?
+ Diet Has Key Role in ADHD Symptoms in Children
+ Home Environment Protects Against Development of Heart Disease Risk Factors After Child Abuse
+ Children in Underserved Communities Are at Increased Risk of Being Admitted to the Pediatric ICU and of Dying There
+ Children’s Physical Activity Levels Fell Below National Guidelines in Wake of Pandemic
+ Potential Pathway Linking Infant Infections to Cardiovascular Disease



Contact Us | Job Listings | Help | Site Map | About Us
Advertising Information | HND Press Release | Submit Information | Disclaimer

Site hosted by Sanchez Productions