Non-invasive Imaging Can Detect Mutations Within a Brain Tumor
Mar 22, 2012 - 11:51:57 AM
(HealthNewsDigest.com) - ATLANTA--Researchers at Winship Cancer Institute have developed a technique for detecting an "oncometabolite," a chemical produced by some brain tumors’ warped metabolism, via non-invasive imaging.
Their approach could allow doctors to know not only that a brain tumor is there, but also that it carries a particular genetic mutation.
The researchers’ technique uses magnetic resonance spectroscopy (MRS) to measure a chemical, 2-hydroxyglutarate, that is scarce in normal tissues. 2-hydroxyglutarate is produced by some types of brain tumors carrying mutations in an enzyme called isocitrate dehydrogenase (IDH).
The results were published this week by the Journal of Molecular Medicine.
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